Eastern District of Missouri

The Eastern District of Missouri, headquartered at the Thomas F. Eagleton United States Courthouse in St. Louis, is the busiest of Missouri's two federal districts with 8 authorized judgeships. St. Louis's legacy as a manufacturing and pharmaceutical hub generates substantial product-liability litigation, including multidistrict proceedings involving major drug makers. The district has been a significant venue for civil rights litigation tied to the St. Louis metropolitan region.